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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: IKHSLGKEIAL SLPSPEGLSL KATPGAAHKL PKKHPERSEL LSHLRHATAQ PASQAGQKRP FSCSFGDHDY CQVLR
Highest antigen sequence identity to the following orthologs - mouse 80%, rat 80%.
PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Peroxisome proliferator-activated receptor gamma coactivator 1-beta; pgc-1 beta; PGC-1-beta; PGC-1-related estrogen receptor alpha coactivator
Gene Aliases: PERC; PGC1; PGC1B; PPARGC1; PPARGC1B
Entrez Gene ID: (Human) 133522
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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