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The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cyclophilin H; CypH; Peptidyl-prolyl cis-trans isomerase H; peptidylprolyl isomerase H (cyclophilin H); PPIase H; Rotamase H; Small nuclear ribonucleoprotein particle-specific cyclophilin H; U-snRNP-associated cyclophilin SnuCyp-20; U-snRNP-associated cyclophilin SunCyp-20; USA-CYP; USA-CyP SnuCyp-20
基因别名: 1100001J08Rik; 2010111B15Rik; 4833408F11Rik; AI464484; CYP-20; CYP20; CYPH; D4Wsu43e; PPIH; RGD1564921; SnuCyp-20; USA-CYP
UniProt ID: (Human) O43447, (Mouse) Q9D868
Entrez Gene ID: (Human) 10465, (Rat) 366461, (Mouse) 66101
分子生物学功能: chaperone