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Invitrogen
PPP1R10 Polyclonal Antibody
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PPP1R10 Antibody (PA5-48110) in WB
Western blot analysis of PPP1R10 in 0.2 mg/mL lysates of HeLa human cervical epithelial carcinoma cell line. Samples were incubated in PPP1R10 polyclonal antibody (Product # PA5-48110) using a dilution of 1 µg/mL. Specific bands were detected for PNUTS at approximately 100-150 kDa (as indicated). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.
产品信息
PA5-48110
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant human PNUTS Pro5-Asn226
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA. Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, which suggests that multiple signaling pathways are involved in carrying out Pol I transcription. RPA40 and RPA16 are subunits of Pol I that associate with each other at an early stage of RNA polymerase I assembly. RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III). RPA40, RPA16 and RPA135 encode the three subunits of RNA polymerase I, respectively. RPA194 is the largest subunit of RNA Pol I and is not a component of Pol II and Pol III.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HLA-C adjacent transcript 53; HLA-C associated transcript 53; MHC class I region proline-rich protein CAT53; p99; Phosphatase 1 nuclear targeting subunit; PNUTSPP1R10; PP1-binding protein of 114 kDa; Protein FB19; protein phosphatase 1, regulatory (inhibitor) subunit 10; protein phosphatase 1, regulatory subunit 10; protein phosphatase I; Protein PNUTS; putative protein phosphatase 1 nuclear targeting subunit; Serine/threonine-protein phosphatase 1 regulatory subunit 10; testis tissue sperm-binding protein Li 67n
基因别名: 2610025H06Rik; CAT53; D17Ertd808e; FB19; p99; PNUTS; PP1R10; PPP1R10; R111
UniProt ID: (Human) Q96QC0, (Rat) O55000, (Mouse) Q80W00
Entrez Gene ID: (Human) 5514, (Rat) 65045, (Mouse) 52040
