Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
PPP1R9B Monoclonal Antibody (K94019_14H11)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
PPP1R9B Antibody (MA5-55631) in WB
Western blot analysis of PPP1R9B in 15 µg of rat brain tissue. Sample was run on 6-18% SDS-PAGE under reducing conditions, blotted onto nitrocellulose membrane, and peroxidase conjugated goat anti-mouse IgG was used as the secondary antibody. PPP1R9B band was visualized using ECL Substrate. Incubation with primary PPP1R9B monoclonal antibody (Product # MA5-55631) at a dilution of 1 µg/mL was used.
产品信息
MA5-55631
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
K94019_14H11
抗原
Recombinant human PPP1R9B (immunogen range is 451-810).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Sequence of this protein is as follows: FSTAPIQVFS TYSNEDYDRR NEDVDPMAAS AEYELEKRVE RLELFPVELE KDSEGLGISI IGMGAGADMG LEKLGIFVKT VTEGGAAHRD GRIQVNDLLV EVDGTSLVGV TQSFAASVLR NTKGRVRFMI GRERPGEQSE VAQLIQQTLE QERWQREMME QRYAQYGEDD EETGEYATDE DEELSPTFPG GEMAIEVFEL AENEDALSPV DMEPEKLVHK FKELQIKHAV TEAEIQQLKR KLQSLEQEKG RWRVEKAQLE QSVEENKERM EKLEGYWGEA QSLCQAVDEH LRETQAQYQA LERKYSKAKR LIKDYQQKEI EFLKKETAQR RVLEESELAR KEEMDKLLDK ISELEGNLQT
靶标信息
Protein phosphatase 1 regulatory subunit 9B (PPP1R9B), also known as Neurabin II or spinophilin, is a gene located on chromosome 17q21.32 that encodes a regulatory protein predominantly expressed in the brain. PPP1R9B is involved in modulating the activity of protein phosphatase 1 (PP1), a crucial enzyme in cellular signaling pathways responsible for dephosphorylation of target proteins. Spinophilin functions by anchoring PP1 to specific subcellular locations, such as synaptic sites, thereby influencing synaptic plasticity, neurotransmission, and signal transduction. This protein is integral to the maintenance and modulation of excitatory synapses, playing a role in cognitive processes including learning and memory. Alterations in PPP1R9B expression or function have been associated with neuropsychiatric disorders and cancer, reflecting its importance in neuronal integrity and its potential role in tumorigenesis. Research into PPP1R9B continues to explore its therapeutic potential in neurological disorders and its utility in understanding phosphatase-related cellular processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: neurabin 2; Neurabin-2; Neurabin-II; Neural tissue-specific F-actin-binding protein II; nuerabin 2; p130; PP1bp134; Protein phosphatase 1 regulatory subunit 9B; protein phosphatase 1, regulatory (inhibitor) subunit 9B; protein phosphatase 1, regulatory subunit 9B; protein phosphatase 1, regulatory subunit 9B, spinophilin; Spinophilin
基因别名: Neb2; PPP1R6; PPP1R9; PPP1R9B; SPINO; Spn
UniProt ID: (Human) Q96SB3, (Rat) O35274
Entrez Gene ID: (Human) 84687, (Rat) 84686
regulation of protein phosphorylation
actin filament organization
dendrite development
cell migration
calcium-mediated signaling
negative regulation of cell growth
regulation of cell proliferation
filopodium assembly
modulation of synaptic transmission
cellular response to morphine
regulation of opioid receptor signaling pathway
regulation of cell growth by extracellular stimulus
cell cycle arrest
regulation of exit from mitosis
RNA splicing
neuron projection development
negative regulation of catalytic activity
