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This antibody is expected to react with mouse, rat, canine, porcine, and bovine samples based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Medium tumor antigen-associated 61 kDa protein; MGC786; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; PP2Ac; PP2Calpha; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; protein phosphatase 2 regulatory subunit A, alpha; protein phosphatase 2, regulatory subunit A, alpha; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; testicular secretory protein Li 1
基因别名: MRD36; PP2A-Aalpha; PP2AAALPHA; PPP2R1A; PR65A
UniProt ID: (Human) P30153
Entrez Gene ID: (Human) 5518
分子生物学功能: phosphatase modulator