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Invitrogen
PPP2R1B Monoclonal Antibody (25GB5610)
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PPP2R1B Antibody (MA570309) in WB
Western blot analysis of PPP2R1B. Samples (HT-1080, HepG2, HeLa, HAP-1, H9C2, C2C12) were incubated with PPP2R1B monoclonal antibody (Product # MA570309) at a dilution of 1:2,500, followed by HRP-conjugated goat anti-mouse secondary antibody (1:20,000) respectively. Image was developed using NaQECL Substrate Kit.
产品信息
MA570309
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
25GB5610
抗原
Recombinant protein of human (19-601) PPP2R1B.
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
靶标信息
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A alpha and PP2A beta. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A alpha and -A beta, PP2A-B alpha and -B beta, PP2A-C alpha and -C beta, and PP2A-B56 alpha and -B56 beta.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PP2A -AR1 beta; PP2A A beta; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta; PP2A, subunit A, PR65-beta isoform; PP2A, subunit A, R1-beta isoform; PP2A-A beta; PP2A-APR65 beta; PP2AA beta; protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform; protein phosphatase 2 regulatory subunit A, beta; protein phosphatase 2, regulatory subunit A, beta; protein phosphatase 2, structural/regulatory subunit A, beta; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
基因别名: PP2A-Abeta; PPP2R1B; PR65B
UniProt ID: (Human) P30154
Entrez Gene ID: (Human) 5519
