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Invitrogen
PPP2R2B/PPP2R2C Polyclonal Antibody
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PPP2R2B/PPP2R2C Antibody (PA5-116862) in WB
Western blot analysis of PPP2R2B/PPP2R2C in extracts of various cell lines. Samples were incubated with PPP2R2B/PPP2R2C Polyclonal antibody (Product # PA5-116862) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116862
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 108-220 of human PPP2R2B/PPP2R2CPPP2R2B (NP_8580602)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.7 mg/mL
规格
70 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: MCF7, Mouse brain, Mouse testis, Rat brain, Rat testis
Immunogen sequence: GDKGGRVVIF QREQESKNQV HRRGEYNVYS TFQSHEPEFD YLKSLEIEEK INKIRWLPQQ NAAYFLLSTN DKTVKLWKVS ERDKRPEGYN LKDEEGRLRD PATITTLRVP VLR
靶标信息
Protein phosphatase 3 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.The B regulatory subunit might modulate substrate selectivity and catalytic activity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BRbeta B-regulatory subunit of protein phosphatase 2A; IMYPNO1; PP2A subunit B isoform B55-beta; PP2A subunit B isoform B55-gamma; PP2A subunit B isoform beta; PP2A subunit B isoform BRB; PP2A subunit B isoform BRgamma; PP2A subunit B isoform gamma; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform PR55-gamma; PP2A subunit B isoform R2-beta; PP2A subunit B isoform R2-gamma; PP2A, subunit B, B-beta isoform; PP2A, subunit B, B-gamma isoform; PP2A, subunit B, B55-beta isoform; PP2A, subunit B, B55-gamma isoform; PP2A, subunit B, BRB isoform; PP2A, subunit B, BRgamma isoform; PP2A, subunit B, PR55-beta isoform; PP2A, subunit B, PR55-gamma isoform; PP2A, subunit B, R2-beta isoform; PP2A, subunit B, R2-gamma isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform
基因别名: 2900026H06Rik; 6330404L05Rik; 6330548O06Rik; E130009M08Rik; IMYPNO; IMYPNO1; PP2A-PR55B; PPP2R2B; PPP2R2C; Pppr2b2; PR52; PR55-BETA; SCA12
UniProt ID: (Rat) P36877, (Mouse) Q6ZWR4, (Mouse) Q8BG02, (Rat) P97888
Entrez Gene ID: (Rat) 60660, (Mouse) 72930, (Mouse) 269643, (Rat) 117256
mitochondrial fission
protein targeting to mitochondrion
signal transduction
spermatid development
brain development
neuron differentiation
regulation of protein phosphatase type 2A activity
positive regulation of neuron apoptotic process
mitochondrial fragmentation involved in apoptotic process
apoptotic process
regulation of catalytic activity
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