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Invitrogen
PPP2R5C Polyclonal Antibody
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PPP2R5C Antibody (PA5-110209) in WB
Western blot analysis of PPP2R5C in extracts of various cell lines. Samples were incubated with PPP2R5C Polyclonal antibody (Product # PA5-110209) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-110209
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human PP2A-B56γ/PR61γ/PP2A-B56γ/PR61γ/PPP2R5C (NP_8487021)
偶联物
形式
Liquid
浓度
0.63 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MLTCNKAGSR MVVDAANSNG PFQPVVLLHI RDVPPADQEK LFIQKLRQCC VLFDFVSDPL SDLKWKEVKR AALSEMVEYI THNRNVITEP IYPEVVHMFA VNMFRTLPPS SNPTGAEFDP EEDEPTLEAA WPHLQLVYEF FLRFLESPDF QPNIAKKYID QKFVLQLLEL FDSEDPRERD FLKTTLHRIY GKFLGLRAYI RKQINNIFYR FIYETEHHNG IAELLEILGS IINGFALPLK EEHKIFLLKV LLPLHKVKSL SVYHPQLAYC VVQFLEKDST LTEPVVMALL KYWPKTHSPK EVMFLNELEE ILDVIEPSEF
靶标信息
Phosphatases are involved in the regulation of MAP kinases.Protein phosphatase 2A (PP2A) is a critical component of the pathway responsible for p38 MAPK up-regulation of SERT catalytic activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B' alpha regulatory subunit; B55-GAMMA; B56/PP2A gamma; Band 8A; IMYPNO; IMYPNO1; MGC23064; MGC33570; PP2A B subunit isoform B'-alpha-3; PP2A B subunit isoform B'-gamma; PP2A B subunit isoform B56-gamma; PP2A B subunit isoform PR61-gamma; PP2A B subunit isoform R5-gamma; PR52; PR55G; protein phosphatase 2 regulatory subunit B', gamma; protein phosphatase 2, regulatory subunit B (B56), gamma isoform; protein phosphatase 2, regulatory subunit B', gamma isoform; Renal carcinoma antigen NY-REN-29; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
基因别名: 2610043M05Rik; 2700063L20Rik; AI060890; AW545884; B56G; C85228; D12Bwg0916e; KIAA0044; mKIAA0044; PPP2R5C; PR61G
UniProt ID: (Human) Q13362, (Mouse) Q60996
Entrez Gene ID: (Human) 5527, (Rat) 691318, (Mouse) 26931
signal transduction
negative regulation of cell proliferation
regulation of phosphatidylinositol 3-kinase signaling
regulation of protein phosphatase type 2A activity
proteasome-mediated ubiquitin-dependent protein catabolic process
proteolysis
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
protein processing
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of catalytic activity
