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Invitrogen
PPP3CB Polyclonal Antibody
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图: 1 / 6
PPP3CB Antibody (PA5-15581) in ICC/IF
Immunofluorescence analysis of PPP3CB was performed using 70% confluent log phase MCF7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with PPP3CB Polyclonal Antibody (Product # PA5-15581) at 5 µg/mL in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-15581
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PPP3CB
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2 mg/mL
规格
800 µg
纯化类型
Size-exclusion - Dialysis, Ammonium sulfate precipitation
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with mouse and rat based on sequence homology.
靶标信息
PPP3CB is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: calcineurin A beta; calcineurin A1; calcineurin A2; CAM-PRP catalytic subunit; CNA beta; PP2BA beta; protein phosphatase 3, catalytic subunit, beta isozyme; protein phosphatase from PCR fragment H32; RP11-345K20.1; unnamed protein product
基因别名: 1110063J16Rik; CALNA2; CALNB; CNA2; Cnab; CnAbeta; PP2Bbeta
UniProt ID: (Human) P16298, (Mouse) P48453
Entrez Gene ID: (Human) 5532, (Mouse) 19056
protein serine/threonine phosphatase activity
calcium ion binding
protein binding
calmodulin binding
hydrolase activity
enzyme binding
protein phosphatase 2B binding
calmodulin-dependent protein phosphatase activity
protein dimerization activity
calcium-dependent protein serine/threonine phosphatase activity
macromolecular complex binding
negative regulation of T cell mediated cytotoxicity
lymphangiogenesis
protein phosphorylation
protein dephosphorylation
response to stress
lysosome organization
heart development
regulation of gene expression
calcium ion regulated exocytosis
negative regulation of signaling
T cell differentiation
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to cytokine
positive regulation of insulin secretion involved in cellular response to glucose stimulus
T cell homeostasis
negative regulation of innate immune response
positive regulation of transcription from RNA polymerase II promoter
skeletal muscle fiber development
regulation of insulin secretion
positive regulation of calcineurin-NFAT signaling cascade
calcineurin-mediated signaling
antibacterial innate immune response
negative regulation of protein localization to nucleus
positive regulation of protein localization to nucleus
regulation of synaptic vesicle endocytosis
positive regulation of calcium ion import across plasma membrane
positive regulation of lysosome organization
negative regulation of calcium ion import across plasma membrane
signal transduction
learning
memory
dephosphorylation
T cell proliferation
T cell activation
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
axon extension
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