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Invitrogen
PPP3CC Polyclonal Antibody
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PPP3CC Antibody (PA5-96770) in WB
Western blot analysis of PPP3CC in extracts of various cell lines. Samples were incubated with PPP3CC Polyclonal antibody (Product # PA5-96770) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-96770
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 373-512 of human PPP3CC (NP_0055962)
偶联物
形式
Liquid
浓度
1.38 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LISDDEAEGS TTVRKEIIRN KIRAIGKMAR VFSILRQESE SVLTLKGLTP TGTLPLGVLS GGKQTIETAT VEAVEAREAI RGFSLQHKIR SFEEARGLDR INERMPPRKD SIHAGGPMKS VTSAHSHAAH RSDQGKKAHS; Positive Samples: Mouse testis, Rat brain
靶标信息
Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcineurin A gamma; Calcineurin, testis-specific catalytic subunit; Calmodulin-dependent calcineurin A subunit gamma isoform; CAM-PRP catalytic subunit; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma); protein phosphatase 3 catalytic subunit gamma; protein phosphatase 3, catalytic subunit, gamma isoform; Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
基因别名: Calnc; PP2BA gamma; Ppp3cc
UniProt ID: (Mouse) P48455
Entrez Gene ID: (Mouse) 19057, (Rat) 171378
