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Invitrogen
PRELP Polyclonal Antibody
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PRELP Antibody (PA5-78631) in IHC (P)
PRELP Polyclonal Antibody detects PRELP protein at secreted on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. PRELP Polyclonal Antibody (Product # PA5-78631) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-78631
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human PRELP. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.95 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: mouse heart
Predicted Reactivity: Human (100%), Rat (91%), Rhesus Monkey (99%), Bovine (91%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 55 kDa leucine-rich repeat protein of articular cartilage; Prolargin; prolargin proteoglycan; Proline-arginine-rich end leucine-rich repeat protein; proline/arginine-rich end leucine-rich repeat protein
基因别名: 7330409J17Rik; MST161; MSTP161; PRELP; SLRR2A
UniProt ID: (Human) P51888, (Mouse) Q9JK53
Entrez Gene ID: (Human) 5549, (Mouse) 116847
