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Invitrogen
PREX2 Polyclonal Antibody
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产品信息
PA5-117672
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (1417-1592aa)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody has been tested in direct-ELISA
靶标信息
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
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生物信息学
蛋白别名: DEP domain containing 2; DEP domain-containing protein 2; P-Rex2; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; protein phosphatase 1, regulatory subunit 129; PtdIns(3,4,5)-dependent Rac exchanger 2
基因别名: 6230420N16Rik; AI316880; AI553603; C030045D06Rik; D430013K02; DEP.2; DEPDC2; P-REX2; PPP1R129; PREX2
UniProt ID: (Human) Q70Z35, (Mouse) Q3LAC4
Entrez Gene ID: (Human) 80243, (Mouse) 109294
