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Recommended positive controls: 293T, Raji.
Predicted reactivity: Mouse (98%), Rat (97%), Pig (98%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PRMT5 (protein arginine N-methyltransferase 5) is an arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. PRMT5 specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3; such methylation is required for the assembly and biogenesis of snRNP core particles.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 72 kDa ICln-binding protein; EC 2.1.1.125; Histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; Jak-binding protein 1; PRMT5; Protein arginine N-methyltransferase 5; Shk1 kinase-binding protein 1 homolog; SKB1 homolog
基因别名: HRMT1L5; IBP72; JBP1; PRMT5; SKB1; SKB1Hs
UniProt ID: (Human) O14744, (Mouse) Q8CIG8
Entrez Gene ID: (Human) 10419, (Mouse) 27374