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PRMT7 Antibody (720143) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized HeLa cells for detection of PRMT-7 using Anti- PRMT-7 Rabbit Polyclonal Antibody (Product # 720143, 1 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of PRMT-7 protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). Panel c) represent... View More
产品信息
720143
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human PRMT7 (aa 301-566)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 0.1% BSA, 30% glycerol
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2576972
产品详细信息
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Bovine, Rabbit and Goat.
靶标信息
Arginine methylation is an irreversible post translational modification which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These proteins include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [Myelin basic protein]-arginine N-methyltransferase PRMT7; FLJ10640; Histone-arginine N-methyltransferase PRMT7; myelin basic protein-arginine N-methyltransferase; PRMT-7; Protein arginine N-methyltransferase 7
基因别名: KIAA1933; PRMT7
UniProt ID: (Human) Q9NVM4
Entrez Gene ID: (Human) 54496
histone-arginine N-methyltransferase activity
S-adenosylmethionine-dependent methyltransferase activity
protein-arginine N-methyltransferase activity
[myelin basic protein]-arginine N-methyltransferase activity
protein-arginine omega-N monomethyltransferase activity
protein-arginine omega-N asymmetric methyltransferase activity
protein-arginine omega-N symmetric methyltransferase activity
histone binding
ribonucleoprotein complex binding
histone methyltransferase activity (H4-R3 specific)
protein modifying enzyme
spliceosomal snRNP assembly
regulation of gene expression by genetic imprinting
transcription, DNA-templated
regulation of transcription, DNA-templated
histone methylation
peptidyl-arginine methylation
peptidyl-arginine methylation, to symmetrical-dimethyl arginine
peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
cell differentiation
histone arginine methylation
DNA methylation involved in gamete generation
regulation of protein binding
histone H4-R3 methylation
