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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 220 kDa U5 snRNP-specific protein; H PRPC8; p220; Pre-mRNA-processing-splicing factor 8; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; spl; Splicing factor Prp8
基因别名: AU019467; D11Bwg0410e; DBF3/PRP8; Prp8; PRPC8; PRPF8; Sfprp8l
UniProt ID: (Mouse) Q8K001
Entrez Gene ID: (Rat) 287530, (Mouse) 192159