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Invitrogen
PRPH2 Polyclonal Antibody
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PRPH2 Antibody (PA5-106336) in ICC/IF
Immunofluorescent analysis of PRPH2 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and PRPH2 polyclonal antibody (Product # PA5-106336) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-106336
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PRPH2(Accession P23942), corresponding to amino acid residues P147-K197.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total PRPH2.
靶标信息
Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: peripherin 2 (retinal degeneration, slow); peripherin 2, homolog of mouse; peripherin, photoreceptor type; Peripherin-2; retinal degeneration 2; Retinal degeneration slow protein; retinal degeneration, slow; retinal degeneration, slow (retinitis pigmentosa 7); retinal peripherin; Tetraspanin-22; Tspan-22
基因别名: AOFMD; AVMD; CACD2; DS; MDBS1; Nmf193; PRPH; PRPH2; Rd-2; Rd2; RDS; RP7; RSRDS; TSPAN22
UniProt ID: (Human) P23942, (Rat) P17438, (Mouse) P15499
Entrez Gene ID: (Human) 5961, (Rat) 25534, (Mouse) 19133
