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产品信息
PA5-27734
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein fragment corresponding to a region within amino acids 142 and 307 of Human PRPS1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545210
产品详细信息
Recommended positive controls: 293T, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (95%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: deafness 2, perceptive, congenital; deafness, X-linked 2, perceptive, congenital; dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1); Phosphoribosyl pyrophosphate synthase I; PPRibP; PRS-I; ribose-phosphate diphosphokinase 1; Ribose-phosphate pyrophosphokinase 1
基因别名: ARTS; CMTX5; DFN2; DFNX1; PPRibP; PRPS1; PRS-I; PRSI
UniProt ID: (Human) P60891
Entrez Gene ID: (Human) 5631
5-phosphoribose 1-diphosphate biosynthetic process
purine nucleobase metabolic process
purine nucleotide biosynthetic process
AMP biosynthetic process
pyrimidine nucleotide biosynthetic process
nervous system development
phosphorylation
organ regeneration
urate biosynthetic process
hypoxanthine biosynthetic process
