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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SGAYFAWKAT AMGKNYVNGK TFLEKRYNED LELEDAIHTA ILTLKESFEG QMTEDNIEVG ICNEAGFRRL TPTEVKDYLA AIA
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha-2; Macropain subunit C3; Multicatalytic endopeptidase complex subunit C3; OTTHUMP00000207364; OTTHUMP00000207366; proteasome alpha 2 subunit; Proteasome component C3; Proteasome subunit alpha type-2; Proteasome subunit alpha-2; PSMA 2
Gene Aliases: HC3; Lmpc3; PSC3; PSMA2
UniProt ID: (Rat) P17220, (Mouse) P49722
Entrez Gene ID: (Rat) 29669, (Mouse) 19166
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