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MA5-15676 targets PTH1R in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15676 immunogen is purified recombinant fragment of human PTH1R expressed in E. Coli.
MA5-15676 detects PTH1R which has a predicted molecular weight of approximately 66kDa.
Parathyroid hormone receptor 1 is a member of the G-protein coupled receptor family. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Parathyroid hormone receptor 1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC138426; MGC138452; Parathyroid hormone 1 receptor; parathyroid hormone receptor; parathyroid hormone receptor 1; Parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related protein receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTHrP-R; PTHrP-receptor; seven transmembrane helix receptor
基因别名: PFE; PTH1R; PTHR; PTHR1
UniProt ID: (Human) Q03431
Entrez Gene ID: (Human) 5745