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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Highest antigen sequence identity to the following orthologs: Mouse- 88%, Rat- 89%.
Sequence of this protein is as follows: RLRPSSVGHL VDHMVHTSPS EVFVNQRSPS STQANSIVLE SSPSQETPGD GKPPALPPKQ SKKNSWNQIH YSHSQQDLES HINETFDIPS SPEKPTPNGG IPHDNLVLIR MKPDENGRFG FNVKGGYDQK MP
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signaling downstream of the glutamate receptors through tyrosine dephosphorylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MEG; Protein-tyrosine phosphatase MEG1; PTP PTPMEG1; Tyrosine-protein phosphatase non-receptor type 4
基因别名: PTPN4
Entrez Gene ID: (Human) 5775