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Invitrogen
PTPRF Polyclonal Antibody
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PTPRF Antibody (PA5-110242) in WB
Western blot analysis of PTPRF in BeWo cells. Samples were incubated with PTPRF Polyclonal antibody (Product # PA5-110242) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-110242
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
形式
Liquid
浓度
2.66 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KNFRVAAAMK TSVLLSWEVP DSYKSAVPFK ILYNGQSVEV DGHSMRKLIA DLQPNTEYSF VLMNRGSSAG GLQHLVSIRT APDLLPHKPL PASAYIEDGR FDLSMPHVQD PSLVRWFYIV VVPIDRVGGS MLTPRWSTPE ELELDELLEA IEQGGEEQRR RRRQAERLKP YVAAQLDVLP ETFTLGDKKN YRGFYNRPLS PDLSYQCFVL ASLKEPMDQK RYASSPYSDE IVVQV
靶标信息
Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ43335; FLJ45062; FLJ45567; LAR; LAR protein; LCA homolog; LCA-homolog; leukocyte antigen-related (LAR) PTP receptor; leukocyte antigen-related tyrosine phosphatase; Leukocyte common antigen related; protein tyrosine phosphatase, receptor type, F polypeptide; PTPRF protein; receptor-linked protein-tyrosine phosphatase LAR; Receptor-type tyrosine-protein phosphatase F
基因别名: AA591035; BNAH2; LAR; LARS; PTPRF; RPTP-LAR
UniProt ID: (Human) P10586, (Mouse) A2A8L5
Entrez Gene ID: (Human) 5792, (Mouse) 19268
protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
heparin binding
protein complex binding
chondroitin sulfate proteoglycan binding
phosphoprotein phosphatase activity
insulin receptor binding
hydrolase activity
phosphatase activity
receptor tyrosine kinase binding
phosphate ion binding
protein phosphatase
protein modifying enzyme
cell adhesion
transmembrane receptor protein tyrosine phosphatase signaling pathway
chemical synaptic transmission
cell migration
neuron projection regeneration
peptidyl-tyrosine dephosphorylation
regulation of axon regeneration
negative regulation of receptor binding
negative regulation of cytokine-mediated signaling pathway
protein dephosphorylation
homophilic cell adhesion via plasma membrane adhesion molecules
signal transduction
nervous system development
negative regulation of cell proliferation
regulation of neuron projection development
dephosphorylation
negative regulation of cell projection organization
negative regulation of epidermal growth factor receptor signaling pathway
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
negative regulation of insulin receptor signaling pathway
positive regulation of dendrite morphogenesis
regulation of synapse structure or activity
negative regulation of neurotrophin TRK receptor signaling pathway
