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Invitrogen
PTPRN2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-50110
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from internal of human PTPRN2 (aa 206-255).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total PTPRN2 protein.
靶标信息
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: an autoantigen in insulin-dependent diabetes mellitus; EC 3.1.3.48; IA-2 beta; IAR/receptor-like protein-tyrosine phosphatase; islet cell autoantigen-related protein; KIAA0387; phogrin; protein tyrosine phosphatase homolog; protein tyrosine phosphatase receptor pi; protein tyrosine phosphatase, receptor type, N polypeptide 2; protein tyrosine phosphatase-NP; PTP IA-2beta; PTP-IA-2beta; transmembrane protein; R-PTP-N2; tyrosine phosphatase IA-2 beta; unnamed protein product
基因别名: 4930425H11Rik; IA-2beta; IA2beta; IAR; ICAAR; mKIAA0387; phogrin; Phol; PTP-NP; PTPRP; R-PTP-N2
UniProt ID: (Human) Q92932, (Mouse) P80560
Entrez Gene ID: (Human) 5799, (Mouse) 19276
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
