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Invitrogen
PTPRT Polyclonal Antibody
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产品信息
PA5-50568
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region derived from internal residues of human Protein tyrosine phosphatase, receptor type, T
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total PTPRT protein.
靶标信息
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: protein tyrosine phosphatase, receptor type, T; R-PTP-T; receptor protein tyrosine phosphatase; receptor protein tyrosine phosphatase-rho; Receptor-type tyrosine-protein phosphatase rho; Receptor-type tyrosine-protein phosphatase T; RP5-1121H13.2; RPTP-rho; RPTPmam4
基因别名: KIAA0283; mKIAA0283; mRPTPrho; PTPRT; R-PTP-T; RPTP-rfo; RPTP-rho; RPTPmam4; RPTPrho
UniProt ID: (Human) O14522, (Mouse) Q99M80
Entrez Gene ID: (Human) 11122, (Mouse) 19281
protein tyrosine phosphatase activity
protein binding
beta-catenin binding
alpha-catenin binding
gamma-catenin binding
cadherin binding
delta-catenin binding
phosphoprotein phosphatase activity
hydrolase activity
thiolester hydrolase activity
phosphatase activity
alpha-actinin binding
extracellular matrix glycoprotein
