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Invitrogen
PTPRZ Monoclonal Antibody (279245)
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PTPRZ Antibody (MA5-23980) in IHC (P)
Immunohistochemical analysis of PTPRZ in immersion fixed paraffin-embedded sections of human brain (cortex). Samples were incubated in PTPRZ monoclonal antibody (Product # MA5-23980) using a dilution of 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cell bodie... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-23980
产品规格
种属反应
Human
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
279245
抗原
E. coli-derived recombinant human PTP beta/zeta/PTPRZ Gly302-Asn754
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: protein tyrosine phosphatase, receptor-type, Z polypeptide 1; protein tyrosine phosphatase, receptor-type, zeta polypeptide 1; protein-tyrosine phosphatase receptor type Z polypeptide 2; receptor-type tyrosine phosphatase beta/zeta; unnamed protein product
基因别名: HPTPZ; HPTPzeta; phosphacan; PTP-ZETA; PTP18; PTPRZ; PTPZ; R-PTP-zeta-2; RPTPB; RPTPbeta
UniProt ID: (Human) P23471
Entrez Gene ID: (Human) 5803
protein dephosphorylation
signal transduction
central nervous system development
learning or memory
neuron projection development
regulation of myelination
peptidyl-tyrosine dephosphorylation
negative regulation of neuron apoptotic process
oligodendrocyte differentiation
positive regulation of oligodendrocyte differentiation
regulation of oligodendrocyte progenitor proliferation
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