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Invitrogen
PURA Polyclonal Antibody
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PURA Antibody (PA5-98103) in WB
Western Blot analysis of PURA using a PURA Polyclonal antibody (Product # PA5-98103) at a concentration of 4.7 µg/mL. Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 35 kDa.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-98103
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Transcriptional activator protein Pur-alpha protein (50-296AA)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
4.71 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Purine-rich single-stranded DNA-binding protein alpha; Transcriptional activator protein Pur-alpha
基因别名: MRD31; NEDRIHF; PUR-ALPHA; PUR1; PURA; PURALPHA
UniProt ID: (Human) Q00577
Entrez Gene ID: (Human) 5813
translation repressor activity, nucleic acid binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
double-stranded DNA binding
double-stranded telomeric DNA binding
single-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
RNA binding
protein binding
purine-rich negative regulatory element binding
SMAD binding
DNA-binding transcription factor binding
transcription regulator inhibitor activity
negative regulation of transcription from RNA polymerase II promoter
DNA replication initiation
regulation of transcription from RNA polymerase II promoter
nervous system development
cell proliferation
positive regulation of cell proliferation
negative regulation of translation
negative regulation of transcription, DNA-templated
lymphocyte proliferation
epithelial cell proliferation
dendritic transport of messenger ribonucleoprotein complex
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