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Invitrogen
Paclitaxel Recombinant Mouse Monoclonal Antibody (2F10)
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Paclitaxel Antibody (MA566384) in SDS-PAGE
SDS-PAGE characterization of Paclitaxel under reducing conditions. Lane M: Protein marker (kDa); Lane TaX: Purified Paclitaxel Recombinant Monoclonal (Product # MA566384). Paclitaxel showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-333.
产品信息
MA566384
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2F10
抗原
Conjugate of TaX hapten and KLH.
偶联物
形式
Liquid
浓度
13 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Paclitaxel is a potent anticancer agent originally derived from the bark of the Pacific yew tree, Taxus brevifolia, and is now produced through semi-synthetic methods due to its limited natural supply. It functions by stabilizing microtubules, thereby inhibiting cell division, which is crucial for its effectiveness against various cancers, including breast, lung, and ovarian cancers. The biosynthesis of paclitaxel involves complex pathways, and recent advances have focused on enhancing its bioavailability and developing novel formulations, such as nanoparticle polymeric micellar paclitaxel, to improve its therapeutic index and reduce side effects. Research continues to explore its applications and production methods to meet the growing demand for this essential medicine. Synonyms for paclitaxel include Taxol, Onxal, Anzatax, Asotax, Bristaxol, Praxel, Paxene, and Paclitaxel Injection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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