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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TrkA/TrkB/TrkC Antibodies

          Osenses

          Pan Trk Polyclonal Antibody

          1 Reference
          View all (7) TrkA/TrkB/TrkC antibodies

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          Cite Pan Trk Polyclonal Antibody

          Pan Trk Polyclonal Antibody

          Product Details

          OST00248G-500UG

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          10-50 µg/mL
          -

          Immunohistochemistry (IHC)

          10-50 µg/mL
          -

          Miscellaneous PubMed (Misc)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from the cytoplasmic domain of mouse TrkA, TrkB, TrkC conjugated to blue carrier protein was used as the antigen
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          PBS

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

          The antigen is homologous in rat, human and zebrafish.

          Specificity of this antibody: pan Trk.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: BDNF-tropomyosine receptor kinase B; BDNF/NT-3 growth factors receptor; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp140trk; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP145-TrkC; High affinity nerve growth factor receptor; neural receptor protein-tyrosine kinase (trkB); neural receptor protein-tyrosine kinase (trkC); Neurotrophic tyrosine kinase receptor type 1; Neurotrophic tyrosine kinase receptor type 2; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 1; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine kinase, receptor, type 3; neurotrophic tyrosine receptor kinase type 2; neurotrophin-3; NT-3 growth factor receptor; Oncogene TRK; p140-TrkA; Slow nerve growth factor receptor; trk; Trk-A; Trk-B; Trk-C; TRK1-transforming tyrosine kinase protein; TrkA neurotrophin receptor; trkA proto-oncogene receptor; TrkB tyrosine kinase; TrkC tyrosine kinase; Tropomyosin-related kinase A; Tropomyosin-related kinase B; Tyrosine kinase receptor; Tyrosine kinase receptor A; tyrosine kinase receptor B; tyrosine kinase receptor C

          View more View less

          Gene Aliases: AW125844; C80751; gp145(trkC); GP145-TrkB; GP145-TrkB/GP95-TrkB; GP145-TrkC; MTC; NTRK1; NTRK2; NTRK3; Ntrk3_tv3; p140-TrkA; RATTRKB1; Tkr; Tkrb; TRK; Trk-A; trk-B; TRK1; TRKA; TRKB; TRKB1; TRKC

          View more View less

          UniProt ID: (Human) P04629, (Human) Q16620, (Human) Q16288, (Mouse) Q3UFB7, (Rat) P35739, (Mouse) P15209, (Rat) Q63604, (Mouse) Q6VNS1, (Rat) Q03351

          View more View less

          Entrez Gene ID: (Human) 4914, (Human) 4915, (Human) 4916, (Mouse) 18211, (Rat) 59109, (Mouse) 18212, (Rat) 25054, (Mouse) 18213, (Rat) 29613

          View more View less

          Function(s)
          transmembrane receptor protein tyrosine kinase activity GPI-linked ephrin receptor activity neurotrophin p75 receptor binding protein binding ATP binding nerve growth factor receptor activity kinase binding protein homodimerization activity neurotrophin binding nerve growth factor binding receptor tyrosine kinase binding brain-derived neurotrophic factor binding brain-derived neurotrophic factor-activated receptor activity p53 binding neurotrophin receptor activity nucleotide binding protein kinase activity protein tyrosine kinase activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups ephrin receptor binding transmembrane signal receptor immunoglobulin superfamily cell adhesion molecule
          Process(es)
          activation of MAPKK activity positive regulation of protein phosphorylation protein phosphorylation microtubule-based movement axon guidance aging learning or memory circadian rhythm negative regulation of cell proliferation response to radiation programmed cell death involved in cell development positive regulation of neuron projection development response to activity peptidyl-tyrosine phosphorylation olfactory nerve development B cell differentiation response to nutrient levels nerve growth factor signaling pathway mechanoreceptor differentiation response to drug positive regulation of programmed cell death negative regulation of neuron apoptotic process positive regulation of GTPase activity response to ethanol positive regulation of Ras protein signal transduction protein autophosphorylation neurotrophin TRK receptor signaling pathway ephrin receptor signaling pathway phosphatidylinositol-mediated signaling sympathetic nervous system development response to axon injury detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain positive regulation of NF-kappaB transcription factor activity response to hydrostatic pressure response to electrical stimulus positive regulation of synapse assembly positive regulation of synaptic transmission, glutamatergic Sertoli cell development axonogenesis involved in innervation behavioral response to formalin induced pain positive regulation of ERK1 and ERK2 cascade cellular response to nicotine cellular response to nerve growth factor stimulus vasculogenesis neuron migration inflammatory response neuromuscular junction development learning long-term memory feeding behavior positive regulation of cell proliferation response to light stimulus positive regulation of gene expression response to auditory stimulus glutamate secretion positive regulation of phosphatidylinositol 3-kinase signaling central nervous system neuron development cerebral cortex development neuron differentiation brain-derived neurotrophic factor receptor signaling pathway positive regulation of peptidyl-serine phosphorylation calcium-mediated signaling using intracellular calcium source neurotrophin signaling pathway regulation of GTPase activity positive regulation of MAPK cascade retinal rod cell development regulation of neurotransmitter secretion oligodendrocyte differentiation peripheral nervous system neuron development positive regulation of axonogenesis regulation of dendrite development regulation of protein kinase B signaling retina development in camera-type eye long-term synaptic potentiation cellular response to amino acid stimulus cellular response to tumor necrosis factor cellular response to brain-derived neurotrophic factor stimulus negative regulation of anoikis activation of MAPK activity negative regulation of protein phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway heart development modulation by virus of host transcription positive regulation of cell migration activation of protein kinase B activity positive regulation of apoptotic process neuron fate specification positive regulation of axon extension involved in regeneration negative regulation of astrocyte differentiation positive regulation of positive chemotaxis response to corticosterone negative regulation of cell death lens fiber cell differentiation cellular response to retinoic acid cochlea development activation of GTPase activity positive regulation of actin cytoskeleton reorganization multicellular organism development nervous system development phosphorylation sensory perception of pain cell differentiation response to nicotine positive regulation of angiogenesis innervation cellular response to growth factor stimulus negative regulation of neuron death regulation of metabolic process regulation of MAPK cascade positive regulation of glucocorticoid receptor signaling pathway
          It has to be done as per old AB suggested Products section.
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