Invitrogen

Paxillin Polyclonal Antibody

Name: Paxillin Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-34910
Availability: InStock

高级验证

查看其他49个Paxillin抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (10)
高级验证 (1)

Paxillin Antibody in Immunocytochemistry (ICC/IF)

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Paxillin Antibody (PA5-34910) in ICC/IF

Immunocytochemistry-Immunofluorescence analysis of Paxillin was performed in MDA-MB-231 cells fixed in 4% paraformaldehyde at RT for 15 min. Green: Paxillin Polyclonal Antibody (Product # PA5-34910) diluted at 1:100. Red: phalloidin staining.

Paxillin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Paxillin Antibody in Immunoprecipitation (IP)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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产品信息

PA5-34910

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:20,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

免疫沉淀 (IP)

1:100-1:500

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein encompassing a sequence within the center region of human Paxillin. The exact sequence is proprietary.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.48 mg/mL

48 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2552260

产品详细信息

Recommended positive controls: 293T, A431, HeLa, HepG2, rat brain, GFP-human Paxillin-transfected 293T, MDA-MB-231.

Predicted reactivity: Mouse (94%), Chicken (82%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。