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Invitrogen
Periostin Monoclonal Antibody (CL12087)
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图: 1 / 7
Periostin Antibody (MA5-44161) in ICC/IF
Immunofluorecent analysis of Periostin in U-138 cells using Periostin Monoclonal Antibody (CL12087) (Product # MA5-44161). Staining shows specific staining in vesicles in green. Microtubule- and nuclear probes are visualized in red and blue, respectively.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-44161
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
CL12087
抗原
Recombinant protein corresponding to Human POSTN
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody solution should be gently mixed before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: LTQPGDWTLF VPTNDAFKGM TSEE
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 92%.
靶标信息
Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor beta 1(TGF beta 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fasciclin I-like; Fasciclin-I like; MGC119510; MGC119511; OSF 2; OSF-2; osteoblast specific factor 2; Osteoblast-specific factor 2; Periostin; PN; RP11 412K4.1; RP11-412K4.1
基因别名: OSF2; POSTN
Entrez Gene ID: (Human) 10631
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
