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Invitrogen
Phenobarbita Recombinant Mouse Monoclonal Antibody (4F6)
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Phenobarbita Antibody (MA566665) in SDS-PAGE
SDS-PAGE characterization of Phenobarbita under reducing conditions. Lane M: Protein marker (kDa); Lane PBA: Purified Phenobarbita Recombinant Monoclonal (Product # MA566665). Phenobarbita showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-675.
产品信息
MA566665
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4F6
抗原
Conjugate of PBA hapten and KLH.
偶联物
形式
Liquid
浓度
7.7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Phenobarbital is a long-acting barbiturate used primarily as an anticonvulsant and sedative-hypnotic medication. It is one of the oldest and most commonly prescribed antiepileptic drugs, effective in managing various types of seizures, including generalized tonic-clonic and partial seizures. Phenobarbital works by enhancing the inhibitory actions of gamma-aminobutyric acid (GABA) on neurotransmission, thereby stabilizing neuronal activity in the brain. Its use extends to the treatment of status epilepticus and febrile seizures in children, although newer antiepileptic drugs have largely replaced it due to concerns about side effects and potential for dependence. As a barbiturate, phenobarbital can induce sedation, dizziness, and cognitive impairment. It also carries a risk for tolerance and addiction, necessitating careful dose management and monitoring. Despite these limitations, phenobarbital remains a valuable option in certain clinical scenarios, particularly in resource-limited settings due to its low cost and broad efficacy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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