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Invitrogen
Phospho-APLF (Ser116) Polyclonal Antibody
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Phospho-APLF (Ser116) Antibody (PA5-105966) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-APLF (Ser116) in human breast tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-APLF (Ser116) polyclonal antibody (Product # PA5-105966) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-105966
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human APLF(Accession Q8IW19), corresponding to amino acid residues around phosphorylated Ser116.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of APLF only when phosphorylated at Ser116.
靶标信息
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks.[supplied by OMIM, Mar 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aprataxin- and PNK-like factor; apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; unnamed protein product; XRCC1-interacting protein 1; zinc finger, CX5CX6HX5H motif containing 1
基因别名: 2010301N04Rik; APFL; C2orf13; PALF; RGD1565557; Xip1; ZCCHH1
UniProt ID: (Human) Q8IW19, (Mouse) Q9D842
Entrez Gene ID: (Human) 200558, (Mouse) 72103, (Rat) 500247
nucleotide binding
DNA-(apurinic or apyrimidinic site) lyase activity
endodeoxyribonuclease activity
protein binding
3'-5' exonuclease activity
histone binding
protein binding involved in protein folding
poly-ADP-D-ribose binding
histone chaperone activity
ADP-D-ribose modification-dependent protein binding
single strand break repair
DNA repair
double-strand break repair
double-strand break repair via nonhomologous end joining
protein folding
cellular response to DNA damage stimulus
embryo implantation
regulation of epithelial to mesenchymal transition
regulation of isotype switching
protein localization to chromatin
DNA repair-dependent chromatin remodeling
regulation of DNA repair
biological_process
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