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Invitrogen
Phospho-Coronin 1B (Ser2) Polyclonal Antibody
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Phospho-Coronin 1B (Ser2) Antibody (PA5-143670) in ICC/IF
Immunocytochemistry analysis of Phospho-Coronin 1B (Ser2) in rabbit spleen fibroblasts treated with Calyculin A. The cells were labeled with rabbit polyclonal Coronin-1B (C-terminus) and Phospho-Coronin 1B (Ser2) polyclonal antibody (Product # PA5-143670), then detected using appropriate secondary antibodies conjugated to Cy3. The antibodies were used in the absence (left) or presence (right) of their respe... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-143670
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Coronin-1B (Ser-2) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding serine 2 in human coronin-1B. This sequence has high homology to the conserved site in rat and mouse coronin-1B and in coronin-1A. However, this sequence has low homology to the conserved region in other coronins.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.25 mg/mL
规格
25 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 1mg/mL BSA, 50% glycerol
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects a 60 kDa* band corresponding to Coronin-1B on SDS-PAGE immunoblots of human A431 or HeLa cells treated with Calyculin A. This band is not observed in control cells and the band observed in Calyculin A-treated cells can be removed with lambda phosphatase treatment.
靶标信息
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: coronin 1b; coronin 2; Coronin-1B; Coronin-2
基因别名: CORO1B
UniProt ID: (Rat) O89046, (Mouse) Q9WUM3
Entrez Gene ID: (Rat) 29474, (Mouse) 23789
cell migration
actin cytoskeleton organization
ruffle organization
negative regulation of Arp2/3 complex-mediated actin nucleation
endothelial cell chemotaxis
wound healing
actin filament bundle assembly
actin filament branching
protein localization to cell leading edge
positive regulation of lamellipodium morphogenesis
cellular response to platelet-derived growth factor stimulus
negative regulation of smooth muscle cell chemotaxis
negative regulation of lamellipodium morphogenesis
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