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This antibody detects endogenous protein at a molecular weight of 78 kDa.
Purity is >95% by SDS-PAGE.
Bone marrow tyrosine kinase (BMX) is a non-receptor tyrosine kinase that belongs to the SRC-related TEC subfamily of tyrosine kinases. It is an important regulator of various cellular processes including apoptosis, cell survival, cellular differentiation, cell migration, and transformation. One family of nonreceptor TKs includes the genes TEC (MIM 600583), TXK (MIM 600058), ITK (MIM 186973), and BTK (MIM 300300). All of these proteins are homologs of the Drosophila Src28 TK and contain an SH3 and SH2 domain upstream of the TK domain.[supplied by OMIM].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Bone marrow tyrosine kinase gene in chromosome X protein; Bone marrow tyrosine kinase gene in chromosome X protein homolog; BTK-like on X chromosome; Cytoplasmic tyrosine-protein kinase BMX; epa3; Epithelial and endothelial tyrosine kinase; ETK; Etk/Bmx cytosolic tyrosine kinase; NTK38; NTK38 tyrosine kinase; TYRO8 protein tyrosine kinase 8
基因别名: BMX; ETK; Etk/Bmx; PSCTK2; PSCTK3; RGD1565643; Tyro8
UniProt ID: (Human) P51813, (Mouse) P97504
Entrez Gene ID: (Human) 660, (Rat) 367786, (Mouse) 12169
分子生物学功能: GTPase-activating protein