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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of EPH B1/3/4 only when phosphorylated at Tyr778/792/774.
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: developmental kinase 2; developmental kinase 5; EK6; ELK-related protein tyrosine kinase; embryonic kinase 2; Eph receptor B2 (ELK-related protein tyrosine kinase); eph tyrosine kinase 2; EPH-like kinase 6; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; ephrin receptor EphB4; hepatoma transmembrane kinase; human embryo kinase 2; mDK-2; neuronally-expressed EPH-related tyrosine kinase; Sek-4; tyrosine kinase MYK-1; tyrosine-protein kinase receptor EPH-2; tyrosine-protein kinase receptor HTK; tyrosine-protein kinase receptor SEK-4; tyrosine-protein kinase TYRO11; tyrosine-protein kinase TYRO6; unnamed protein product
基因别名: 9330129L11; b2b2412Clo; C130099E04Rik; Cek10; Cek6; CMAVM2; EK2; ELK; Elkh; Ephb2; EPHT2; Erk; ETK2; HEK2; Hek6; HFASD; HTK; LMPHM7; mDK-5; MDK2; MDK5; MYK1; NET; Sek4; TYRO11; TYRO6
UniProt ID: (Human) P54762, (Human) P54753, (Human) P54760, (Mouse) Q8CBF3, (Rat) P09759, (Mouse) P54754, (Mouse) P54761
Entrez Gene ID: (Human) 2047, (Human) 2049, (Human) 2050, (Mouse) 270190, (Rat) 24338, (Rat) 287989, (Mouse) 13845, (Mouse) 13846, (Rat) 686310