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Invitrogen
Phospho-FBP1 (Tyr265) Polyclonal Antibody
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Phospho-FBP1 (Tyr265) Antibody (PA5-105335) in WB
Western blot analysis of Phospho-FBP1 (Tyr265) in mouse kidney tissue (Lane 1: treated with phospho-blocking peptide; Lane 2: treated with non-phospho-blocking peptide). Samples were incubated with Phospho-FBP1 (Tyr265) polyclonal antibody (Product # PA5-105335).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-105335
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FBP1(Accession P09467), corresponding to amino acid residues around phosphorylated Tyr265.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of FBP1 only when phosphorylated at Tyr265.
靶标信息
Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 3; EC 3.1.3.11; FBP 1; FBPase 1; FBPase liver; fructose 1,6-bisphosphatase (EC 3.1.3.11); fructose-1; fructose-1,6- biphosphatase 1; fructose-1,6-bisphosphatase isozyme 3; Fructose-16- biphosphatase; GIG17; growth-inhibiting protein 17; liver FBPase; unnamed protein product
基因别名: FBP; Fbp-2; Fbp2; Fbp3; Fdp
UniProt ID: (Human) P09467, (Mouse) Q9QXD6, (Rat) P19112
Entrez Gene ID: (Human) 2203, (Mouse) 14121, (Rat) 24362
negative regulation of transcription from RNA polymerase II promoter
carbohydrate metabolic process
fructose metabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
regulation of gluconeogenesis
negative regulation of cell growth
response to nutrient levels
cellular response to insulin stimulus
negative regulation of glycolytic process
negative regulation of Ras protein signal transduction
cellular response to magnesium ion
cellular response to cAMP
cellular response to xenobiotic stimulus
cellular hyperosmotic salinity response
cellular hypotonic salinity response
cellular response to raffinose
cellular response to phorbol 13-acetate 12-myristate
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