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Invitrogen
Phospho-FOXM1 (Ser35) Polyclonal Antibody
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Phospho-FOXM1 (Ser35) Antibody (PA5-105197) in ICC/IF
Immunocytochemistry analysis of Phospho-FOXM1 (Ser35) in Hela cells (4h of LPS treatment). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-FOXM1 (Ser35) polyclonal antibody (Product # PA5-105197) 1:200 and mouse anti-beta tubulin antibody (1:200) for 1 hour at 37°C. An AlexaFluor594 conjugated goat ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-105197
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FOXM1(Accession Q08050), corresponding to amino acid residues around phosphorylated Ser35.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of FOXM1 only when phosphorylated at Ser35.
靶标信息
FOXM1 (forkhead box protein M1) is a transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. FOXM1 plays a role in the control of cell proliferation and DNA break repairs participating in the DNA damage checkpoint response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell proliferation-inducing gene 29 protein; FKH L16; FKHL 16; forkhead box M1-D; forkhead homolog 16; Forkhead like 16; Forkhead, drosophila, homolog-like 16; forkhead-related protein FKHL16; FOXM 1; FOXM 1c; hepatocyte nuclear factor 3 forkhead homolog 11; hepatocyte nuclear factor-3/fork head homolog 11A; winged helix transcription factor; HFH 11; HNF 3; HNF-3/fork-head homolog 11; HNF3; INS 1; INS-1 winged helix; INS1; M-phase phosphoprotein 2; MPHOSPH 2; MPM 2; MPM-2 reactive phosphoprotein 2; MPP 2; PIG 29; TGT3; transcription factor Trident; trident; unnamed protein product; winged helix transcription factor; hepatocyte nuclear factor-3/fork head homolog 11B; winged-helix factor from INS-1 cells; winged-helix transcription factor Trident
基因别名: Fkh16; FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH-11B; HFH11; HNF-3; INS-1; MPHOSPH2; Mpm2; MPP-2; MPP2; PIG29; TRIDENT; WIN
UniProt ID: (Human) Q08050
Entrez Gene ID: (Human) 2305, (Mouse) 14235, (Rat) 58921
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein kinase binding
phosphatidylinositol 3-kinase regulatory subunit binding
phosphatidylinositol 3-kinase catalytic subunit binding
sequence-specific DNA binding
protein serine/threonine kinase binding
transcription regulatory region sequence-specific DNA binding
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of mitotic cell cycle
positive regulation of cell proliferation
positive regulation of epithelial to mesenchymal transition
DNA damage response, signal transduction by p53 class mediator
negative regulation of stress-activated MAPK cascade
regulation of cell proliferation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of Ras protein signal transduction
regulation of cell cycle
regulation of reactive oxygen species metabolic process
positive regulation of double-strand break repair
vasculogenesis
liver development
response to gonadotropin
response to cAMP
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