7TM Antibodies

Phospho-IP Prostacyclin Receptor (Ser324, Ser328) Polyclonal Antibody

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问题与答案

问题与答案

问题与答案

抗体检测数据 (1)

Phospho-IP Prostacyclin Receptor (Ser324, Ser328) Antibody in Western Blot (WB)

Phospho-IP Prostacyclin Receptor (Ser324, Ser328) Antibody in Western Blot (WB)

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Phospho-IP Prostacyclin Receptor (Ser324, Ser328) Antibody (7TM0345B) in WB

Agonist-induced Serine324/Serine328 phosphorylation of the IP Prostacyclin Receptor. Upper panel, HEK293 cells stably expressing the IP Prostacyclin receptor (IP) were either not exposed or exposed to 10 µM Treprostinil for 30 minutes. Cells were lysed and immunoblotted with the anti-pS324/pS328-IP antibody (7TM0345B) at a dilution of 1:1,000. Lower panel, blot was stripped and reprobed with an phosphorylat... View More

Phospho-IP Prostacyclin Receptor (Ser324, Ser328) Antibody in Western Blot (WB)

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Phospho-IP Prostacyclin Receptor (Ser324, Ser328) Antibody in Western Blot (WB) — Agonist-induced Serine324/Serine328 phosphorylation of the IP Prostacyclin Receptor. Upper panel, HEK293 cells stably expressing the IP Prostacyclin receptor (IP) were either not exposed or exposed to 10 µM Treprostinil for 30 minutes. Cells were lysed and immunoblotted with the anti-pS324/pS328-IP antibody (7TM0345B) at a dilution of 1:1,000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-IP antibody to confirm equal loading of the gel.

Immunogen image

Phospho-IP Prostacyclin Receptor (Ser324, Ser328) Polyclonal Antibody

Immunogen Image Phospho-IP Prostacyclin Receptor (Ser324, Ser328) Polyclonal Antibody

产品信息

7TM0345B

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic phosphopeptide derived from human IP around the phosphorylation site of Ser324/Ser328.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

Dulbecco's PBS, pH 7.4

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: IP receptor; PGI receptor; PGI2 receptor; Prostacyclin receptor; Prostaglandin I2 receptor; Prostanoid IP receptor

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基因别名: IP; PRIPR; PTGIR

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UniProt ID: (Human) P43119

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Entrez Gene ID: (Human) 5739

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guanyl-nucleotide exchange factor activity prostacyclin receptor activity G-protein coupled receptor

inflammatory response G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger adenylate cyclase-activating G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration cell-cell signaling negative regulation of platelet-derived growth factor receptor signaling pathway positive regulation of cAMP biosynthetic process response to lipopolysaccharide positive regulation of GTPase activity positive regulation of cAMP-mediated signaling negative regulation of smooth muscle cell proliferation cellular response to prostaglandin D stimulus