Phospho-JAK2 (Tyr1007, Tyr1008) Recombinant Rabbit Monoclonal Antibody (K01_4U18)

nucleotide binding protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding kinase activity transferase activity protein kinase binding heme binding receptor activator activity type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding identical protein binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding protein C-terminus binding transferase activity, transferring phosphorus-containing groups

activation of MAPKK activity activation of cysteine-type endopeptidase activity involved in apoptotic process response to oxidative stress signal transduction enzyme linked receptor protein signaling pathway G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration JAK-STAT cascade tyrosine phosphorylation of STAT protein STAT protein import into nucleus positive regulation of cell proliferation negative regulation of cell proliferation intrinsic apoptotic signaling pathway in response to oxidative stress hormone-mediated signaling pathway negative regulation of cardiac muscle cell apoptotic process positive regulation of cell-substrate adhesion positive regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine phosphorylation cytokine-mediated signaling pathway negative regulation of cell-cell adhesion myeloid cell differentiation cell differentiation erythrocyte differentiation positive regulation of cell migration axon regeneration mineralocorticoid receptor signaling pathway positive regulation of insulin secretion response to lipopolysaccharide positive regulation of phosphoprotein phosphatase activity positive regulation of interleukin-1 beta production positive regulation of tumor necrosis factor production positive regulation of protein import into nucleus, translocation response to hydroperoxide tumor necrosis factor-mediated signaling pathway host programmed cell death induced by symbiont response to tumor necrosis factor histone H3-Y41 phosphorylation intracellular signal transduction interleukin-12-mediated signaling pathway peptidyl-tyrosine autophosphorylation tyrosine phosphorylation of Stat3 protein tyrosine phosphorylation of Stat5 protein tyrosine phosphorylation of Stat1 protein positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein activation of JAK2 kinase activity positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of DNA binding negative regulation of DNA binding negative regulation of neuron apoptotic process positive regulation of nitric oxide biosynthetic process positive regulation of cell differentiation negative regulation of heart contraction positive regulation of transcription from RNA polymerase II promoter response to antibiotic protein autophosphorylation platelet-derived growth factor receptor signaling pathway regulation of inflammatory response positive regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation positive regulation of cell activation positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of nitric-oxide synthase biosynthetic process interferon-gamma-mediated signaling pathway growth hormone receptor signaling pathway JAK-STAT cascade involved in growth hormone signaling pathway positive regulation of growth hormone receptor signaling pathway mammary gland epithelium development response to interleukin-12 cellular response to lipopolysaccharide cellular response to dexamethasone stimulus extrinsic apoptotic signaling pathway activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway positive regulation of apoptotic signaling pathway immune system process protein phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway phosphorylation cell migration chromatin modification regulation of cell adhesion innate immune response response to granulocyte macrophage colony-stimulating factor microglial cell activation positive regulation of cytokine production adaptive immune response chromatin organization chromatin remodeling transcription from RNA polymerase II promoter apoptotic process immune response cell adhesion mesoderm development positive regulation of platelet activation regulation of cell-cell adhesion actin filament polymerization lipopolysaccharide-mediated signaling pathway positive regulation of interferon-gamma production positive regulation of interleukin-17 production positive regulation of natural killer cell proliferation post-embryonic hemopoiesis cellular response to interleukin-3 interleukin-5-mediated signaling pathway collagen-activated signaling pathway interleukin-23-mediated signaling pathway interleukin-3-mediated signaling pathway granulocyte-macrophage colony-stimulating factor signaling pathway erythropoietin-mediated signaling pathway thrombopoietin-mediated signaling pathway positive regulation of T cell proliferation positive regulation of protein import into nucleus positive regulation of tyrosine phosphorylation of STAT protein activation of Janus kinase activity regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of MAPK cascade post-translational protein modification T-helper 1 cell differentiation positive regulation of MHC class II biosynthetic process regulation of nitric oxide biosynthetic process regulation of JAK-STAT cascade positive regulation of JAK-STAT cascade regulation of alpha-beta T cell activation modulation of synaptic transmission positive regulation of NK T cell proliferation positive regulation of protein kinase B signaling positive regulation of SMAD protein import into nucleus negative regulation of growth hormone receptor signaling pathway interleukin-6-mediated signaling pathway positive regulation of leukocyte proliferation interleukin-35-mediated signaling pathway cellular response to virus positive regulation of cold-induced thermogenesis defense response to symbiont negative regulation of cytokine production involved in inflammatory response positive regulation of platelet aggregation positive regulation of intracellular signal transduction positive regulation of growth factor dependent skeletal muscle satellite cell proliferation positive regulation of epithelial cell apoptotic process positive regulation of vascular smooth muscle cell proliferation regulation of postsynapse to nucleus signaling pathway negative regulation of 3'-UTR-mediated mRNA stabilization positive regulation of T-helper 17 type immune response