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Invitrogen
Phospho-KLF5 (Ser303) Polyclonal Antibody
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Phospho-KLF5 (Ser303) Antibody (PA5-105317) in ICC/IF
Immunofluorescent analysis of Phospho-KLF5 (Ser303) in HeLa cells(4h of LPS treatment). Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Phospho-KLF5 (Ser303) polyclonal antibody (Product # PA5-105317) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-105317
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KLF5(Accession Q13887), corresponding to amino acid residues around phosphorylated Ser303.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of KLF5 only when phosphorylated at Ser303.
靶标信息
KLF5 is a member of the Kruppel-like factor subfamily of zinc finger proteins. It contains three C2H2-type zinc fingers at the carboxyl-terminus that preferentially bind to cis-DNA elements that are GC rich. KLF5 is a transcription activator that promotes cell proliferation and oncogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (intestinal Kruppel-like factor; basic transcription element binding protein 2; basic transcription element binding protein BTEB2; basic transcription element-binding protein 2; BTE-binding protein 2; colon krueppel-like factor; colon kruppel-like factor; epididymis secretory sperm binding protein; GC box binding protein 2; intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; Kruppel like factor 5; Kruppel-like factor 5; Kruppel-like factor 5 (intestinal); RP11-505F3.5; testis-specific transcript; tKLF5; transcription factor; transcription factor BTEB2; unnamed protein product
基因别名: 4930520J07Rik; BTEB2; CKLF; IKLF
UniProt ID: (Human) Q13887, (Mouse) Q9Z0Z7
Entrez Gene ID: (Human) 688, (Rat) 84410, (Mouse) 12224
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
MRF binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
gene expression
regulation of gene expression
skeletal muscle satellite cell differentiation
satellite cell activation involved in skeletal muscle regeneration
myotube differentiation involved in skeletal muscle regeneration
skeletal muscle cell differentiation
skeletal muscle tissue regeneration
positive regulation of fat cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
intestinal epithelial cell development
positive regulation of transcription by transcription factor localization
cellular response to leukemia inhibitory factor
cellular response to endothelin
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