Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Phospho-LTK/ALK (Tyr672, Tyr1278) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
Phospho-LTK/ALK (Tyr672, Tyr1278) Antibody (PA5-99574) in WB
Western blot analysis of Phospho-LTK/ALK (Tyr672, Tyr1278) in myeloma cells heat-shock treated (left lane: treated with blocking peptide). Samples were incubated with Phospho-LTK/ALK (Tyr672, Tyr1278) polyclonal antibody (Product # PA5-99574).
产品信息
PA5-99574
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human LTK(Accession P29376), corresponding to amino acid residues around phosphorylated Tyr672.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of LTK/ALK only when phosphorylated at Tyr672/Tyr1278.
靶标信息
The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD246; CD246 antigen; leukocyte receptor tyrosine kinase; Leukocyte tyrosine kinase receptor; mutant anaplastic lymphoma kinase; npm-alk; Protein tyrosine kinase 1; tyrosine kinase-1
基因别名: ALK; CD246; LTK; NBLST3; Tcrz; TYK1
UniProt ID: (Human) Q9UM73, (Mouse) P97793, (Human) P29376, (Mouse) P08923
Entrez Gene ID: (Human) 238, (Mouse) 11682, (Human) 4058, (Mouse) 17005
NF-kappaB-inducing kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
protein binding
ATP binding
identical protein binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
activation of MAPK activity
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
cell proliferation
phosphorylation
peptidyl-tyrosine phosphorylation
NIK/NF-kappaB signaling
regulation of apoptotic process
protein autophosphorylation
neuron development
positive regulation of NF-kappaB transcription factor activity
protein phosphorylation
nervous system development
positive regulation of cardiac muscle cell apoptotic process
positive regulation of neuron projection development
phosphatidylinositol 3-kinase signaling
negative regulation of apoptotic process
cellular response to retinoic acid
