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Antibody detects endogenous levels of MST3 only when phosphorylated at Thr18.
STK24 (MST3) is a serine/threonine kinase that is a member of the GCK subfamily of STE20-like proteins. The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: epididymis secretory protein Li 95; Mammalian STE20-like protein kinase 3; mammalian sterile twenty 3 kinase; MST-3; OTTHUMP00000018594; RP11-111L24.5; serine/threonine kinase 24 (STE20 homolog, yeast); Serine/threonine-protein kinase 24; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3
基因别名: 1810013H02Rik; C76483; HEL-S-95; MST-3; MST3; MST3B; RGD1561742; STE20; STK24; STK3
UniProt ID: (Human) Q9Y6E0, (Mouse) Q99KH8, (Rat) B0LT89
Entrez Gene ID: (Human) 8428, (Mouse) 223255, (Rat) 361092