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Invitrogen
Phospho-MYL2 (Ser19) Recombinant Rabbit Monoclonal Antibody (RM484)
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Phospho-MYL2 (Ser19) Antibody (MA562160) in WB
Western Blot analysis of mouse heart tissue lysate using Phospho-MYL2 (Ser19) recombinant monoclonal antibody (Product # MA562160) at 1:1,000 dilution. The phospho-specificity of RM484 was verified by peptide blocking using a control non-phosphopeptide or phosphopeptide targeting residue Ser19.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA562160
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
RM484
抗原
A phospho-peptide corresponding to human Phospho-Myl2 (Ser19).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
Conc. Not Determined
纯化类型
Protein A
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody reacts to Myl2 (Myosin Light Chain 2v) only when phosphorylated at Ser19. There is no cross-reactivity to Myl2 that is not phosphorylated. This antibody reacts to human, mouse or rat Phospho-Myl2 (Ser19).
靶标信息
Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiac myosin light chain 2; cardiac ventricular myosin light chain 2; DKFZp779C0562; MLC2; MYL2; myosin light chain phosphatase; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; S15D myosin regulatory light chain 2; slow cardiac myosin regulatory light chain 2; T160D myosin regulatory light chain 2; unnamed protein product; ventricular myosin light chain 2
基因别名: CMH10; MFM12; MLC-2; MLC-2s/v; MLC-2v; MLC2
UniProt ID: (Human) P10916
Entrez Gene ID: (Human) 4633
regulation of the force of heart contraction
regulation of striated muscle contraction
heart development
actin filament-based movement
negative regulation of cell growth
muscle cell fate specification
cardiac myofibril assembly
ventricular cardiac muscle tissue morphogenesis
heart contraction
cardiac muscle contraction
positive regulation of the force of heart contraction
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