Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Phospho-PLCg1 (Tyr783) Recombinant Rabbit Monoclonal Antibody (5I7E8)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
Phospho-PLCg1 (Tyr783) Antibody (MA5-55320) in WB
Western Blot analysis of various lysates using Phospho-PLCg1 (Tyr783) Recombinant Monoclonal Antibody (Product # MA5-55320) at 1:2,000 dilution. NIH/3T3 cells were treated by PDGF (100 ng/mL) at 37&(8)451; for 30 minutes after serum-starvation overnight. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk i... View More
产品信息
MA5-55320
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5I7E8
抗原
A synthetic phosphorylated peptide around Y783 of human Phospho-PLC gamma 1.
偶联物
形式
Liquid
浓度
0.26 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
RRID
产品详细信息
Immunogen Sequence: GFYVE
靶标信息
The mammalian Phospholipase Cg (PLCg) family has two closely related proteins, PLCg1 and PLCg2. The PLCg isozymes have the core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains and one SH3 domain. In response to extracellular stimuli, such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCg. Activated PLCg catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce the metabolic second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; cell differentiation and embryonic development; EC 3.1.4.11; OTTHUMP00000178982; Phosphoinositide phospholipase C-gamma-1; phospholipase C-1; Phospholipase C-gamma-1; Phospholipase C2; PLC gamma1; PLC-gamma-1; PLC2I
基因别名: AI894140; Cded; Plc-1; Plc-gamma1; Plcg-1; Plcg1
UniProt ID: (Mouse) Q62077
Entrez Gene ID: (Mouse) 18803
phosphatidylinositol phospholipase C activity
signal transducer activity
insulin receptor binding
neurotrophin TRKA receptor binding
calcium ion binding
protein binding
phosphoric diester hydrolase activity
hydrolase activity
protein kinase binding
receptor tyrosine kinase binding
glutamate receptor binding
metal ion binding
phosphoprotein binding
phospholipase
in utero embryonic development
lipid metabolic process
calcium ion transport
signal transduction
epidermal growth factor receptor signaling pathway
protein secretion
phospholipid catabolic process
positive regulation of epithelial cell migration
lipid catabolic process
cell migration
calcium-mediated signaling
inositol trisphosphate biosynthetic process
intracellular signal transduction
positive regulation of blood vessel endothelial cell migration
positive regulation of angiogenesis
T cell receptor signaling pathway
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
regulation of store-operated calcium channel activity
