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Invitrogen
Phospho-PRK1/PRK2 (Thr774, Thr816) Polyclonal Antibody
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Phospho-PRK1/PRK2 (Thr774, Thr816) Antibody (PA5-118729) in ICC/IF
Immunocytochemistry analysis of Phospho-PRK1/PRK2 (Thr774, Thr816) in A549 cells (H2O2 treatment). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-PRK1/PRK2 (Thr774, Thr816) polyclonal antibody (Product # PA5-118729) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugate... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-118729
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PKN1(Accession Q16512), corresponding to amino acid residues around phosphorylated Thr774.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of PRK1/2 only when phosphorylated at Thr774/816.
靶标信息
Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiolipin-activated protein kinase Pak2; p140 kinase; PKN gamma; protease-activated kinase 1; protease-activated kinase 2; protein kinase C-like 1; protein kinase C-like 2; protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase PKN; protein kinase PKN-alpha; protein-kinase C-related kinase 1; protein-kinase C-related kinase 2; serine-threonine kinase N; serine-threonine protein kinase N; serine/threonine kinase; serine/threonine protein kinase N; unnamed protein product
基因别名: DBK; PAK-1; Pak-2; PAK1; PAK2; PKN; PKN-ALPHA; PRK1; PRK2; PRKCL1; PRKCL2; PRO2042; STK7
UniProt ID: (Human) Q16512, (Human) Q16513, (Rat) Q63433
Entrez Gene ID: (Human) 5585, (Human) 5586, (Rat) 29355, (Rat) 207122
chromatin binding
transcription coactivator activity
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein kinase C binding
protein binding
ATP binding
small GTPase binding
histone kinase activity (H3-T11 specific)
histone binding
histone deacetylase binding
androgen receptor binding
protein serine kinase activity
RNA binding
protein tyrosine kinase activity
kinase activity
cadherin binding
RNA polymerase binding
B cell homeostasis
B cell apoptotic process
negative regulation of protein phosphorylation
regulation of germinal center formation
regulation of immunoglobulin production
renal system process
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
epithelial cell migration
negative regulation of B cell proliferation
intracellular signal transduction
post-translational protein modification
positive regulation of transcription, DNA-templated
spleen development
regulation of cell motility
positive regulation of cytokinesis
apical junction assembly
positive regulation of viral genome replication
positive regulation of mitotic cell cycle
vascular endothelial cell response to laminar fluid shear stress
regulation of androgen receptor signaling pathway
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