Invitrogen

Phospho-RCC1 (Ser11) Polyclonal Antibody

Name: Phospho-RCC1 (Ser11) Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-106204
Availability: InStock

查看其他22个RCC1抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

Phospho-RCC1 (Ser11) Antibody in Western Blot (WB)

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Phospho-RCC1 (Ser11) Antibody (PA5-106204) in WB

Western blot analysis of Phospho-RCC1 (Ser11) in K562 cell lysate (absence (-) or presence (+) of non-phospho and phospho peptide). Samples were incubated with Phospho-RCC1 (Ser11) polyclonal antibody (Product # PA5-106204).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image Phospho-RCC1 (Ser11) Polyclonal Antibody

产品信息

PA5-106204

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human RCC1(Accession P18754), corresponding to amino acid residues around phosphorylated Ser11.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

sequential chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2817602

产品详细信息

Antibody detects endogenous levels of RCC1 only when phosphorylated at Ser11.

靶标信息

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

仅用于科研。不用于诊断过程。未经明确授权不得转售。