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Invitrogen
Phospho-ROC1 (Thr9) Polyclonal Antibody
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Phospho-ROC1 (Thr9) Antibody (PA5-105076) in WB
Western blot analysis of Phospho-ROC1 (Thr9) in 293 cell lysate (Lane 1: treated with phospho-blocking peptide; Lane 2: treated with non-phospho-blocking peptide). Samples were incubated with Phospho-ROC1 (Thr9) polyclonal antibody (Product # PA5-105076).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-105076
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RBX1(Accession P62877), corresponding to amino acid residues around phosphorylated Thr9.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of RBX1 only when phosphorylated at Thr9.
靶标信息
This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase RBX1; E3 ubiquitin-protein transferase RBX1; Protein ZYP; Rbx1; Regulator of cullins 1; RING finger protein 75; RING-box protein 1; ROC1
基因别名: 1500002P15Rik; AA517855; RBX1; RNF75; ROC1
UniProt ID: (Mouse) P62878
Entrez Gene ID: (Mouse) 56438, (Rat) 300084
ubiquitin-protein transferase activity
protein binding
eukaryotic initiation factor 4E binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
NEDD8 transferase activity
protein complex binding
ubiquitin-ubiquitin ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
cullin family protein binding
ubiquitin protein ligase binding
ubiquitin-protein ligase
protein modifying enzyme
DNA repair
ubiquitin-dependent protein catabolic process
protein monoubiquitination
cellular response to DNA damage stimulus
protein ubiquitination
protein catabolic process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
protein neddylation
proteasome-mediated ubiquitin-dependent protein catabolic process
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