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Invitrogen
Phospho-RPA2 (Thr21) Recombinant Rabbit Monoclonal Antibody (4I3A0)
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Phospho-RPA2 (Thr21) Antibody (MA5-35876) in WB
Western blot analysis of Phospho-RPA2 (Thr21) in extracts of C6 cells. Samples were incubated with Phospho-RPA2 (Thr21) Monoclonal antibody (Product # MA5-35876) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. C6 cells were treated by Calyculin A (100 nM) at 37°C for 30 minutes after serum-starvation overnight. Lysates/proteins: 25 µg per... View More
产品信息
MA5-35876
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4I3A0
抗原
A synthetic phosphorylated peptide around T21 of human RPA2 (P15927)
偶联物
形式
Liquid
浓度
0.43 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GYTQS
靶标信息
Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HSSB; p32; p32-subunit of replication protein A; p34; Replication factor A protein 2; Replication protein A 32 kDa subunit; Replication protein A 32kDa subunit; Replication protein A 34 kDa subunit; Replication protein A 34kDa subunit; replication protein A2, 32kDa; RF-A protein 2; RFA; RP-A p32; RP-A p34; RP21C; RP4-547C9.3; RpLP1; RpP2
基因别名: REPA2; RP-A p32; RP-A p34; RPA2; RPA32; RPA34
UniProt ID: (Human) P15927, (Rat) Q63528
Entrez Gene ID: (Human) 6118, (Rat) 59102
telomere maintenance
double-strand break repair via homologous recombination
DNA replication
base-excision repair
nucleotide-excision repair
mismatch repair
regulation of double-strand break repair via homologous recombination
mitotic G1 DNA damage checkpoint
regulation of DNA damage checkpoint
G1/S transition of mitotic cell cycle
telomere maintenance via recombination
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
translesion synthesis
nucleotide-excision repair, DNA incision
interstrand cross-link repair
error-prone translesion synthesis
DNA damage response, detection of DNA damage
error-free translesion synthesis
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator
