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Invitrogen
Phospho-Raptor (Ser792) Polyclonal Antibody
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Phospho-Raptor (Ser792) Antibody (PA5-118730) in IHC (P)
Immunohistochemical analysis of Phospho-Raptor (Ser792) in Rat heart tissue using a Phospho-Raptor (Ser792) polyclonal antibody (Product # PA5-118730). The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the seconda... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-118730
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RPTOR(Accession Q8N122), corresponding to amino acid residues around phosphorylated Ser792.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of Raptor only when phosphorylated at Ser792.
靶标信息
Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Raptor; Regulatory-associated protein of mTOR; unnamed protein product
基因别名: KIAA1303; KOG1; Mip1; RAPTOR; RGD1311784; RPTOR
UniProt ID: (Human) Q8N122
Entrez Gene ID: (Human) 57521, (Rat) 287871
protein binding
protein kinase binding
protein serine/threonine kinase inhibitor activity
protein kinase activator activity
protein binding, bridging
small GTPase binding
macromolecular complex binding
14-3-3 protein binding
enzyme-substrate adaptor activity
RNA polymerase III type 1 promoter DNA binding
RNA polymerase III type 2 promoter DNA binding
RNA polymerase III type 3 promoter DNA binding
TFIIIC-class transcription factor binding
protein complex binding
autophagosome assembly
regulation of cell growth
positive regulation of endothelial cell proliferation
cytoplasmic translation
cellular response to DNA damage stimulus
regulation of cell size
cellular response to starvation
response to xenobiotic stimulus
regulation of autophagy
negative regulation of autophagy
regulation of cell communication
regulation of signaling
positive regulation of cell growth
cellular response to nutrient levels
TOR signaling
positive regulation of TOR signaling
social behavior
TORC1 signaling
positive regulation of osteoclast differentiation
positive regulation of glycolytic process
positive regulation of transcription from RNA polymerase III promoter
negative regulation of translational initiation
positive regulation of translational initiation
positive regulation of lipid biosynthetic process
protein localization to lysosome
regulation of biological quality
cellular response to amino acid stimulus
cellular response to leucine
cellular response to glucose stimulus
cellular response to hypoxia
cellular response to osmotic stress
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of odontoblast differentiation
positive regulation of TORC1 signaling
positive regulation of pentose-phosphate shunt
cell growth
regulation of phosphorylation
positive regulation of protein serine/threonine kinase activity
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