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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
In direct ELISAs, less than 1% cross-reactivity with recombinant mouse (rm) Plexin A2 and rmPlexin A3 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Plex 1; plexin 1; plexin-1; Plexin-A1; Semaphorin receptor NOV
基因别名: 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; PlexA1; PLXN1; PLXNA1
UniProt ID: (Mouse) P70206
Entrez Gene ID: (Mouse) 18844