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Invitrogen
Pozelimab Recombinant Human Monoclonal Antibody
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Pozelimab Antibody (MA5-42235) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human C5 protein expressed in CHO cells using a Pozelimab biosimilar monoclonal antibody (Product # MA5-42235). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-42235
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG4, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human C5
偶联物
形式
Liquid
浓度
3.36 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.5
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Pozelimab is an investigational fully human monoclonal antibody, invented using Regeneron's proprietary VelocImmune technology, which aims to block the complement signaling pathway by binding to complement factor C5. It also prevents the destruction of red blood cells (hemolysis) that causes paroxysmal nocturnal hemoglobinuria and other disease symptoms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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